Thursday, August 27, 2020

The Influence of Family Functioning on Eating Disorders Essay -- Relat

The Influence of Family Functioning on Eating Disorders Understanding the etiology of a dietary problem is maybe the most confounded issue encompassing the malady, as prodding separated reason and outcome can be incredibly troublesome. This issue turns out to be quickly obvious while analyzing family factors related with dietary problems. Examination over the previous decade has concentrated to a great extent on distinguishing family factors that possibly add to the advancement of a dietary issue in an individual, and further refining these attributes into models for the â€Å"anorexic family† or the â€Å"bulimic family.† Identifying an example of explicit family chance components would be an incredibly valuable instrument in perceiving those powerless for building up a dietary issue. While the exploration has been not able to paint an altogether complete image of family attributes, certain characteristics surface as run of the mill to the eating scattered family. Tragically, a significant part of the current writing on fam ily factors and dietary problems depends upon correlational information, as controlled investigations are hard to lead inside a family setting. Alert should in this manner be applied to such discoveries, as one can't expect causality; in light of carefully correlational examinations alone, it can't be resolved whether the family condition caused the dietary problem, or whether the dietary problem prompted family brokenness. All things considered, it stays valuable to look at any critical variables that rise up out of the writing so as to build understanding about every potential factor affecting the advancement of dietary issues. In spite of the fact that the two of them fall into the regular continuum of dietary issues, anorexia nervosa (confining subt... ...(1986). Bulimia: evaluation of eating, Mental modification, and familial qualities. Worldwide Journal of Eating Disorders, 5(5), 865-878. Scalf-McIver, L. and Thompson, J.K. (1989). Family associates of bulimic qualities in school females. Diary of Clinical Psychology, 45(3), 467-472. Harsh, S.L., Dixon, K.L., Jones, D., Lake, M., Nemzer, E., and Sansone, R. (1989). Family Condition in anorexia and bulimia. Universal Journal of Eating Disorders, 8(1), 25-31. Thienemann, M. and Steiner, H. (1993). Family condition of eating scattered and discouraged young people. Universal Journal of Eating Disorders, 14(1), 43 48. Walsh, B.T. and Garner, D.M. (1997). Indicative issues. In D.M. Accumulate and P.E. Garfinkel (Eds.), Handbook for the Treatment of Eating Disorders (pp. 25-33). New York: The Guilford Press.

Saturday, August 22, 2020

Radiocarbon Dating - Reliable but Misunderstood

Radiocarbon Dating - Reliable yet Misunderstood Radiocarbon dating is a standout amongst other realized archeological dating methods accessible to researchers, and the numerous individuals in the overall population have at any rate known about it. Be that as it may, there are numerous misguided judgments about how radiocarbon functions and how dependable a method it is. Radiocarbon dating was created during the 1950s by the American scientist Willard F. Libby and a couple of his understudies at the University of Chicago: in 1960, he won a Nobel Prize in Chemistry for the development. It was the principal outright logical strategy at any point designed: in other words, the method was the first to permit a specialist to decide to what extent back a natural item kicked the bucket, regardless of whether it is in setting or not. Short of a date stamp on an article, it is as yet the best and generally precise of dating methods formulated. How Does Radiocarbon Work? Every single living thing trade the gas Carbon 14 (C14) with the environment around them-creatures and plants trade Carbon 14 with the climate, fish and corals trade carbon with broke down C14 in the water. For the duration of the life of a creature or plant, the measure of C14 is consummately offset with that of its environmental factors. At the point when a life form kicks the bucket, that balance is broken. The C14 in a dead life form gradually rots at a known rate: its half life. The half-existence of an isotope like C14 is the time it takes for half of it to rot away: in C14, at regular intervals, half of it is no more. Along these lines, in the event that you measure the measure of C14 in a dead living being, you can make sense of to what extent prior it quit trading carbon with its environment. Given generally unblemished conditions, a radiocarbon lab can quantify the measure of radiocarbon precisely in a dead life form for up to 50,000 years back; from that point forward, theres insufficient C14 left to gauge. Tree Rings and Radiocarbon There is an issue, in any case. Carbon in the environment vacillates with the quality of earths attractive field and sun oriented movement. You need to recognize what the climatic carbon level (the radiocarbon store) resembled at the hour of a living beings demise, so as to have the option to ascertain how much time has gone since the life form passed on. What you need is a ruler, a dependable guide to the repository: as it were, a natural arrangement of items that you can safely nail a date to, measure its C14 substance and along these lines build up the standard supply in a given year. Luckily, we do have a natural item that tracks carbon in the environment on a yearly premise: tree rings. Trees keep up carbon 14 harmony in their development rings-and trees produce a ring for consistently they are alive. In spite of the fact that we dont have any 50,000-year-old trees, we do have covering tree ring slows down to 12,594 years. Along these lines, at the end of the day, we have a really strong approach to align crude radiocarbon dates for the latest 12,594 years of our planets past. In any case, before that, solitary fragmentary information is accessible, making it exceptionally hard to authoritatively date anything more established than 13,000 years. Solid appraisals are conceivable, yet with enormous/ - factors. The Search for Calibrations As you would envision, researchers have been endeavoring to find other natural items that can be dated safely consistently since Libbys revelation. Other natural informational collections analyzed have included varves (layers in sedimentary stone which were set down every year and contain natural materials, profound sea corals, speleothems (cavern stores), and volcanic tephras; yet there are issues with every one of these techniques. Cavern stores and varves can possibly incorporate old soil carbon, and there are up 'til now uncertain issues with fluctuating measures of C14 in sea corals. Starting during the 1990s, an alliance of specialists drove by Paula J. Reimer of the CHRONO Center for Climate, the Environment and Chronology, at Queens University Belfast, started constructing a broad dataset and adjustment instrument that they previously called CALIB. Since that time, CALIB, presently renamed IntCal, has been refined a few timesas of this composition (January 2017), the program is currently called IntCal13. IntCal joins and fortifies information from tree-rings, ice-centers, tephra, corals, and speleothems to think of an altogether improved adjustment set for c14 dates somewhere in the range of 12,000 and 50,000 years back. The most recent bends were endorsed at the 21st International Radiocarbon Conference in July of 2012. Lake Suigetsu, Japan Inside the most recent couple of years, another potential hotspot for additional refining radiocarbon bends is Lake Suigetsu in Japan. Lake Suigetsus every year shaped silt hold definite data about natural changes in the course of recent years, which radiocarbon authority PJ Reimer accepts will be in the same class as, and maybe better than, tests centers from the Greenland Ice Sheet. Specialists Bronk-Ramsay et al. report 808 AMS dates dependent on dregs varves estimated by three distinctive radiocarbon research centers. The dates and relating ecological changes guarantee to make direct relationships between's other key atmosphere records, permitting analysts, for example, Reimer to finely align radiocarbon dates between 12,500 to the functional furthest reaches of c14 dating of 52,800. Constants and Limits Reimer and partners call attention to that IntCal13 is only the most recent in adjustment sets, and further refinements are normal. For instance, in IntCal09s alignment, they found proof that during the Younger Dryas (12,550-12,900 cal BP), there was a shutdown or if nothing else a lofty decrease of the North Atlantic Deep Water development, which was without a doubt an impression of environmental change; they needed to toss out information for that period from the North Atlantic and utilize an alternate dataset. We should see some intriguing outcomes with regards to the not so distant future. Sources and Further Information Bronk Ramsey C, Staff RA, Bryant CL, Brock F, Kitagawa H, Van der Plicht J, Schlolaut G, Marshall MH, Brauer A, Lamb HF et al. 2012. A total earthly radiocarbon record for 11.2 to 52.8 kyr B.P. Science 338:370-374.Reimer PJ. 2012. Environmental science. Refining the radiocarbon time scale. Science 338(6105):337-338.Reimer PJ, Bard E, Bayliss A, Beck JW, Blackwell PG, Bronk Ramsey C, Buck CE, Cheng H, Edwards RL, Friedrich M et al. . 2013. IntCal13 and Marine13 Radiocarbon Age Calibration Curves 0â€50,000 Years cal BP. Radiocarbon 55(4):1869â€1887.Reimer P, Baillie M, Bard E, Bayliss A, Beck J, Blackwell PG, Bronk Ramsey C, Buck C, Burr G, Edwards R et al. 2009. IntCal09 and Marine09 radiocarbon age adjustment bends, 0-50,000 years cal BP. Radiocarbon 51(4):1111-1150.Stuiver M, and Reimer PJ. 1993. Expanded C14 information base and modified Calib 3.0 c14 age adjustment program. Radiocarbon 35(1):215-230.

Friday, August 21, 2020

How To Earn Extra Money Via Unique Job Referral Platform Jobket

How To Earn Extra Money Via Unique Job Referral Platform â€" Jobket Make Money Online Queries? Struggling To Get Traffic To Your Blog? Sign Up On (HBB) Forum Now!How To Earn Extra Money Via Unique Job Referral Platform â€" JobketUpdated On 24/07/2019Author : HBB Guest AuthorTopic : BusinessShort URL : https://hbb.me/2LU6Mag CONNECT WITH HBB ON SOCIAL MEDIA Follow @HellBoundBlogA side income makes you feel empowered and well off when you already have something else to do. Doesn’t earning some extra money without a lot of hustle and bustle sound superficial?Well, it is time that we can make it real.Ever wondered how to earn some extra monetary rewards by not slogging day and night? Or earning a backup income to pay off your bills?Well, that is exactly what Jobket offers you!Jobket is a platform that empowers you to enter into its unique job referral program and earn rewards.Perplexed about what a job referral program really means? Let’s find out.Primarily, a job referral program is a system which allows employers to find talented candidates with the help of their employees’ networks. It basically allows employees of the companies to undertake a silent part of course of action of recruitment of the company.A job referral platform is considered as one of the most successful and creative programs that has shown tremendous success. Many top notch companies look out for such referral programs to hire ideal candidates.But, there is one idiosyncratic feature that separates Jobket’s job referral program. Under their program, you can refer good candidates to multitudinous companies.So, you don’t have to be an employee of the company for referring a candidate to it. You can simply refer a good candidate directly for as many companies as you want via Jobket.First, let’s see why you should enter into a job referral program:HELP YOUR FRIEND OR FAMILY MEMBERWell, it is rightly said, “A friend in need is a friend indeed.”Supporting a friend might seem hard but you can now do your bit and help the person in need.Referring cand idates is the best way to help a friend or family member looking for jobs to find the perfect job. Your friend will have a higher chance of getting hired and finding the right place for himself.A job referral program has a brilliant, high conversion rate. A candidate is more likely to be hired via referrals than those hired via traditional recruitment procedure.EARN REWARDSRefer and earn rewards for every successful referral! All you’ve to do is refer an ideal candidate for a job posting and your job is done.If hired, your account will be credited with rewards. Even the minimum that you earn with Jobket is good enough to be called an additional income. Isn’t this an extremely attractive incentive?Making references doesn’t require you to spend chunks of money. Referrals on Jobket are made for free! Yes, no investment at all!The platform is definitely a great source of encouragement to find ideal candidates.And guess what? There is no restriction to the number of referrals that you can make. So, sign up for innumerable number of referrals.HELP THE EMPLOYERSWith you referring good candidates, employers are able to bring on board some brilliant employees. The program also helps the company to identify talent for positions that are not easy to fill.Human Resources Manager spends months in filling a job opening. Also, the costs and time involved in a recruitment process gets reduced as the entire process gets simpler.The company saves a lot of time that would have been utilized in scrutinizing and screening applications and conducting tests and interviews. The referral program is just the policy to lessen the baggage of heavy burden on the shoulders of human resource professionals.READArbitao: Dawn of the new era of Arbitrage tradingIt helps companies to find a pool of talent that would be of good quality since they are referred by people.Now, let’s suppose a company receives an order and needs to hire talented and skilled people. The conventional route of r ecruitment would take up as long as a month and company would end up losing the massive order it bagged.In such a situation, referral programs come to the rescue.Since the referred candidates are family members of friends, there are higher chances of them being highly productive and contributing to the timely achievement of goals of the company.So, it shoots up the interests of the company to hire an awesome, engaging workforce.Recruitment through referrals is as up as 10-20%. Job Referral program is a win-win for all three parties involved Companies, Potential employees and You.By doing as simple a thing as referring, you are benefitting so many people. With Jobket, offering you this unique feature, let’s turn to it and see what’s in store.Now, let’s how you can enter into the job referral program on Jobket!Suppose you want to refer your family member for the position of senior Digital Marketing manager, who has an experience of about 3-4 years. Follow the 4-step formula of referral.REGISTERSign up on Jobket and create your account with fundamental personal details to find preferred jobs for referring. Next time you visit the platform, all you’ve to do is log in to and activate your account.BROWSENow, you can search for jobs in Digital Marketing using parameters such as job location, work position, work experience, etc. Check out job descriptions and requirements of multiple companies. Filter companies that you think your family member is suited for.APPLY AND REFEROnce you are sure that the skill set of the family member matches with the job description posted by the company, you can proceed.Apply by using the family member’s job descriptions either on social networking platforms like WhatsApp, Facebook, email or LinkedIn or by simply, referring on Jobket’s website.EARNIf the candidate referred gets hired by the company, you will be rewarded. A minimum of Rs. 40000 cash prize will be honoured on Jobket. Who doesn’t appreciate a special advantag e?Not just monetarily, but emotionally and psychologically also, you are earning recognition and praise from the employers and your family members, now the selected employees of the company.Now that you know the secret to earn additional rewards, without wasting much time, start referring! Be a part of this sound unique job referral program of Jobket.Nakul having experience of Digital Industry in marketing, branding communication solutions, interactive technology development, managing integrated campaigns, project management, App marketing and business development. Launched  www.jobket.in  a unique referral job platform that brings out quality in the hiring process!  Jobket is a platform that allows users to find suitable jobs for yourself and your family friends.

Monday, May 25, 2020

Essay on The Outbreak of World War I - 1150 Words

The Outbreak of World War I On the 1st of August 1914 World War One, also known as the Great War, started. The main countries involved were: Germany, Italy, Austria-Hungary, Britain, France and Russia. World War One ended at 11am on 11th November 1918. In 1919, Lloyd George of England, Orlando of Italy, Clemenceau of France and Woodrow Wilson from the US met to discuss how Germany was to be made to pay for the damage World War One had caused. They decided to create the Treaty of Versailles. In this there were a total of 440 clauses. The first 26 clauses dealt with the establishment of the League of Nations. The remaining 414 clauses spelled out Germanys punishment. This makes it seem that Germany†¦show more content†¦This caused tension between Britain and Germany. The war should just of been between Germany and France because of Alsace Lorraine but Germany got other countries involved. Germany was worried that France and Russia would become Allies and attack Germany. As a result Germany and Russia became Allies first. But Germany insulted Russia and Russia became Allies with France. If this hadn’t of happened there would be no chance of Russia and France even thinking about attacking Germany. Germany got very paranoid and therefore created the â€Å"Schlieffen Plan† which takes its name from its author, Alfred Graf von Schlieffen (1833 – 1913). Schlieffen argued that if war took place it was vital that France was defeated and as quickly as possible. If this happened, Britain and Russia would be unwilling to carry on fighting. Schlieffen calculated that it would take Russia six weeks to organize its large army for an attack on Germany. Therefore, it was vitally important to force France to surrender before Russia was ready to use all its forces. Schlieffens plan involved using 90% of Germanys armed forces to attack France. Fearing the French army on the border with Germany, Schlieffen suggested a quicker attack through Belgium. The rest of the German Army would be sent to defensive positions in the east toShow MoreRelatedThe Outbreak Of World War I1799 Words   |  8 Pagesmany years, causes and driving forces leading to the outbreak of World War I have been argued and disputed. Historians and experts have many different ideas and opinions that may have triggered war. Nationalism, militarism, and imperialism may all have played a role in the coming of World War I, but decisions made by European leaders in the summer of 1914 directly accelerated the conflict. Nationalism was strong in many countries until World War I approached. Countries throughout Europe attempted toRead MoreGermany is Responsible for the Outbreak of World War I972 Words   |  4 PagesHaving suffered the untimely deaths of its emperors William I and Frederick II in the year 1888, the Second Reich was forced to hand political guidance over to a young leader named William II during a time of increasing yet unstable German expansionism. William I possessed a set of social and political plans that stood opposing to the ambitious plans of autocratic chancellor, Otto Von Bismarck and the past chancellors. Following Bismarck’s resignation at the emperor’s army-supported request, WilliamRead MoreEssay on The Realist Theory and The Outbreak of World War I1289 Words   |  6 Pages The realism theory describes World War One the best because it is â€Å"based on the view that describes the individual as primarily fearful, selfish and power seeking† (Mingst, 2011). WWI was initially a war between two countries, Austria-Hungary and Serbia; but due to assassinations, the strength of alliances, binds by treaties, and increasing security dilemma, more and more countries entered the war until it manifested into a complete World War. Countries increased their weaponry and made other nationsRead MoreOutbreak of World War I and Germanys Responsibility Essay2798 Words   |  12 PagesOutbreak of World War I and Germanys Responsibility The War Guilt clause has been called the historical controversy par excellence[1]. At the end of the war article 231 explicitly placed the guilt for all loss and damage of the war on the defeated Germany and her allies. This clause was bitterly denied by Germany and has been a subject of keen debate ever since. The issuing of the blank cheque to Austria in 1914, their strong will to war, the aggressive SchlieffenRead MoreThe Alliance Pathology Of Chain Ganging Responsible For The First Outbreak Of World War I Essay2433 Words   |  10 Pagesresponsible for the first outbreak of the First World War? I agree only to a large extent that the alliance pathology of ‘chain-ganging’ was responsible for the first outbreak of World War I (WWI). I believe that entrapment is the main reason to why the war actually happened. Apart from chain-ganging, there were also other factors that had contributed to the escalation of the war. In this essay I will be discussing the various factors that have led to the outbreak of WWI. Firstly, I will be defining whatRead MoreTo What Extent Does the Impact of World War I Explain the Outbreak of the Two Revolutions in 1917 ?1374 Words   |  6 Pagesof World War I explain the outbreak of the two revolutions in 1917 ? To a certain extent, the First World War was a major contributing factor to the two revolutions that took place in 1917, the February and October Revolution. The war worsened the issues that already existed in Russia and also highlighted the lack of leadership shown by the Tsar and the Provisional Government set up after the February Revolution and also the Tsars military command over the army during the war. However, World WarRead MoreWas the Outbreak of General War in 1914 Inevitable After the Assassination of Arch Duke Franz Ferdinand?1705 Words   |  7 PagesWas the outbreak of general war in 1914 inevitable after the assassination of Arch Duke Franz Ferdinand? Various different factors led to the outbreak of the first World War- a war which incorporated all human, economic and military resources available to achieve total victory over the enemy. Roughly, the causes can be classified into long term (Franco-Prussian War, Imperialism, Alliance System, Anglo- German Naval Arms Race, etc.), short term (Morrocan Crisis, Agadir Crisis, Bosnian Crisis, BalkanRead MoreDevry Hist410 Midterm Exam729 Words   |  3 Pagesproduct/devry-hist410-midterm-exam/ Contact us at: SUPPORT@ACTIVITYMODE.COM DEVRY HIST410 MIDTERM EXAM Question 1. Question : (TCO 1, 2) Analyze how imperialism and militarism contributed to the outbreak of World War I. Use historical examples to support your answer. Of the various causes of World War I, which do you think was the most important, and why? Question 2. Question : (TCO 5, 6) Identify and analyze the first two Russian Revolutions of 1917. Use historical examples to support yourRead MoreTo What Extent Was Responsible For The Outbreak Of The World War1626 Words   |  7 PagesAfter the First World War (1914-1919), the world was faced with the questions - who was responsible and what was reason for the outbreak of the war. Ultimately it was agreed on the 28 June 1919 that â€Å"the Allied and Associated Governments affirm and Germany accepts the responsibility of Germany and her allies for causing all the loss and damage† from the First World War. However, there have been many other interpretations on whom and what was responsible for the war. On the one hand, some historiansRead MoreSignificance of the Nazi Soviet Non Aggression Pact1124 Words   |  5 PagesPact was extremely significant in regards to the outbreak of war in Europe in 1939, however there were several other factors that also led to the outbreak of WWII. These factors inc lude; the allied policy of appeasement, the failure the League of Nations and Collective Security and the aggressive nature of Nazi and Italian foreign policy. The signing of the 1939 Nazi-Soviet Non-Aggression Pact was extremely significant in regards to the outbreak of war in Europe. Both Germany and Russia possessed

Thursday, May 14, 2020

How to Teach the Present Perfect for ESL Students

The present perfect is one of the most difficult tenses to learn for students. Teaching the present perfect effectively involves making sure students understand that the present perfect in English is always connected in some way to the present moment in time. Many languages including French, German, Spanish and Italian use the present perfect for past events. The present perfect in English covers what happens from a past moment to the present moment in time. Establishing this connection in students minds early will help students avoid mistakes. It helps to divide usage into three major areas: 1) From the past until now: Ive lived in New York for twenty years. 2) Life experience: Ive visited every state in the country. 3) Recent past events that influence the present moment: Ive just had lunch. Start by Speaking about Your Experiences Introduce the present perfect by providing three short situations One about life experiences, one speaking about some things that started in the past and continue into the present. Finally, also illustrate the present perfect for events that influence the present moment in time. Speak about yourself, your family or your friends. Life Experience: Ive visited many countries in Europe. Ive been to Germany and France a few times. My wife has also been in Europe quite a lot. However, our daughter has never visited.Past to Present: My friend Tom has a number of hobbies. Hes played chess for more than fifteen years. Hes surfed since he was a little boy, and hes practiced the art of the Japanese tea ceremony since September.Recent Events that Influence the Present:  Wheres Pete? I think hes gone to lunch, but hes been away for about ten minutes. I know hes been to the bank this afternoon so hes probably decided he needs a nice meal.  Ask students about the differences in these forms. Once the differences have been understood, return to your short scenarios and ask students related questions using the present perfect.Life Experience: Ive visited many countries in Europe. Which countries have you visited? Have you ever been to XYZ?Past to Present: My friend Tom has a number of hobbies. Hes played chess for more th an fifteen years. Which hobbies do you have? How long have you done them?Recent Events that Influence the Present:  What have we just studied? Have you understood the form? Explaining the Present Perfect Using the verbs youve introduced, quickly ask students the infinitive form for each verb. (i.e. Which verb is gone? - go, Which verb is bought? - buy, etc.). After having studied the past simple, students should recognize that many past verbs in -ed whereas others have irregular forms. Introduce the past participle form use in the present perfect. Its a good idea to provide an irregular verb sheet for future reference. Use three timelines showing the differences between usages: life experience, past to present, and recent events. At this point in the curriculum, students should easily be able to switch between positive, negative and question forms. However, its important to point out that questions in the present perfect are most often formed with How long for past to present usage, and Have you ever..? for life experiences. Finally, for present perfect that affects the present moment, its important that students understand the differences between the time expressions just, yet and already as well as for and since for past to present. Comprehension Activities Each of these uses of the present perfect can be practiced through present perfect role plays and reading comprehension activities. Its also a good idea to compare and contrast time expressions used for the present perfect and past simple. Present perfect worksheets and quizzes focusing on differences asking students to choose between the present perfect or the past simple will also help. To practice switching between the present perfect and the simple past practice short conversations with Have you ever...? followed by a question asking for specifics with when, or where. Have you ever been to France? - Yes, I have.When did you go there?Have you bought a car? - Yes, I haveWhen did you buy one? Challenges with the Present Perfect Common challenges with the present perfect include: Use of present perfect for events that happened in the pastSwitching between present perfect and past simple fluidlyUse of yet and already in questions, negative and positive formsUse of since with dates and for with periods of time

Wednesday, May 6, 2020

Italian Renissance and the Reformation - 1005 Words

The Renaissance and Reformation were two very important periods of time in European history that included change in culture and religion. The Renaissance happened before the reformation. The Renaissance was the rebirth of art, literature, and architecture. The reformation focused mainly on reforming the Catholic Church from its evil ways. Out of the Catholic Church came the protestant church. There were many different characteristics of the Renaissance. The main one is that society had a secular, or worldly, view. This can be proved by how their art was changed. They stopped painting religious things and painted the human body. Other main points are that recovery from the Black Plague and decline of church power led to interest†¦show more content†¦John Calvin was another leader in the Protestant church. He was originally Catholic and switched to Protestantism. He agreed with Luther on most things but put more emphasis on the â€Å"power, grace, and glory of God.† He believed in predestination. A belief that God determines in advance who is saved and who is to be damned. This religion would be called Calvinism, named after the founder. He also began the Reformation in Geneva, Switzerland. His reform was that there would be government inside the church, but the church would not rule the government. Another religion that broke off was the Anabapt ists. They were radicals who disliked the power given to the state through the reformation. They believed in spiritual rebirth in adulthood. They also believed that all believers were equal and that there was a complete separation of church and state. They had no political authority over them and were not allowed to bear arms. The Church of England broke away from the Catholic Church because Henry VIII wanted an annulment which the Catholic Church would not give him. Therefore he broke off and made the act of supremacy. It said that the king was taken, accepted, and reputed as supreme head of the Church of England. The start of the Catholic reformation was because of the spread of Protestantism. In the 16th century Catholicism had rejuvenation. The three chief pillars of this reformation were: 1. TheShow MoreRelatedItalian Renissance and the Reformation1233 Words   |  5 Pagesauthors began to deal with general questions of the soul. Dante wrote about the soul’s jo urney to salvation. Petrarch, another renowned author from Italy, began to write epics and sonnets; he later became known as the â€Å"Father of The Italian Renaissance†. Aside from the Italian peak of literature, there was also a sudden interest in classical art. Previously, all artwork was pertaining to religion. However there were some creators who dared to oppose the status quo. Michelangelo, a famous sculptor, painterRead MoreItalian Renissance and the Reformation Essay example1452 Words   |  6 PagesThe European Renaissance was a turning point in the way people saw art, literature, and architecture. These new views soon led to the Reformation, or the reforming of the Catholic Church. These changes led Europe out of the middle ages and into modern times. The Renaissance began after Europe began recovering from the Black Death. Anyone who had survived was just happy to be alive and started focusing more on material things, rather than religious ones. Another reason the focus shifted from religious

Tuesday, May 5, 2020

Extended Response Case Study-Free-Samples for Students-Myassignment

Question: Taking into account the role of the myelin sheath and the nodes of Ranvier, explain how APs are propagated along an axon, in a healthy subject, and how this is changed in MS. Answer: Nervous System The axons of neurons often are myelinated i.e. they are wrapped around by a sheath of myelin. Myelin is a protein-lipid complex, which is formed by Schwan Cells of in the Central Nervous System when they wrap their membrane around the axon, eventually locked together by a membrane protein, P0. Nodes of Ranvier are the portions of the axon that are not being enveloped by the myelin i.e. these about 1m periodic gaps of separated by 1mm are unmyelinated. Myelin acts as insulation to nerve impulse conduction. Nerve impulses are sent between neurons which is the only mode of communication for the nervous system. Electronic potentials that can produce propagated disturbances are called action potentials or nerve impulses. The nerve impulses are produced due to change in ionic conduction across the cell membrane of the neurons. The potential of nerve cells are found to be negative inside relative to outside; it is about -70mV. When the neuron is stimulated a series of potential changes occu r across its membrane and the stimulus thus propagates through the axon to another adjacent neuron. Depolarization increases the membrane potential to +35mV and again reverses and falls rapidly causing to reach the resting depolarized state. In unmyelinated nerve fibres local circuits of ion current are produced in the active regions of the neuron which is stimulated; the local circuit thus produced can depolarize the adjacent part of the membrane which continues in s sequential fashion (Arancibia-Carcamo Attwell, 2014). Conversely, in myelinated neurons ion exchange is allowed only at the Nodes of Ranvier and rest of the axon is insulated by myelin itself. This increases the speed of transmission of impulse through the axon. When an impulse reaches a Node of Ranvier it cannot flow through the high-resistance myelin sheath instead depolarizes the membrane at the next Node of Ranvier about 1mm away from it. Thus myelin increases the length constant i.e. the distance an ion travels before leaking out of the membrane by increasing the membrane resistance and thus resulting in insulation of the neuron. Further myelin decreases the capacitance of the membrane by separating the opposite charges across the two sides of the mem brane by a considerable distance. Thus in myelinated neurons impulse flows in a jumping fashion from one Node to the next which is termed as Saltatory Conduction. Multiple Sclerosis is an idiopathic, autoimmune, inflammatory disorder of the Central Nervous System that causes patchy destruction of the myelin sheath of the neurons. The destruction of the myelin sheath results in delayed or blocked conduction of impulses through the affected neurons leading to several neurodegenerative symptoms. Further the damage of myelin causes patches of scar tissues at various regions of the Brain and Spinal Cord and hence the name Multiple Sclerosis (Scleroses meaning scar tissue) (Dendrou, Fugger Friese, 2015). The impairment of nerve impulse conduction can affect physiological functions such as movement, speech or sight. Diagnosis at early stages of the disease prognosis is very difficult which causes delay in commencement of treatment. Endocrine System Metabolism is one of the most significant physiological processes necessary for the sustenance if life. Each and every cell of the human body undergoes various levels of metabolism to perform the fundamental bodily functions. Thyroid gland plays a key role in this context by regulating the level of metabolism in the cells required for the optimal functioning of the same. The hormones secreted by the thyroid gland are Thyroxine (T4) and triiodothyronine (T4), which primarily regulates the oxygen consumption of cells, lipid and carbohydrate metabolism, thermogenesis, growth and nervous system development. Thus they play a pivotal role in growth and maturity and deregulation of the hormone levels can lead to severe disorders. Hence, the hormone secretion is intensely regulated to maintain normal body functioning. Thyroid stimulating hormone or Thyrotropin secreted from the anterior pituitary regulates the secretion of the thyroid gland. It is a tropic hormone and secretion of Thyrotropi n in turn is regulated by Thyrotropin releasing hormone secreted from the paraventricular nucleus of the hypothalamus. Circulating thyroid hormones have feedback effects at hypothalamic and pituitary levels thus completing the Hypothalamus pituitary thyroid axis to maintain optimum levels of both the thyroid hormones in circulating blood (Ortiga?Carvalho, Chiamolera, Pazos?Moura Wondisford, 2016). Increased secretion and hence occurrence of thyroid hormones in the circulating blood results in decreased secretion of Thyrotropin and Thyrotropin releasing hormone and the opposite occurs when thyroid hormones levels are low in circulating blood. Thyroid hormones levels are maintained at a very narrow range by the three glands, failure of any of them causes excess or too less production of thyroid hormones resulting in hyperthyroidism or hypothyroidism respectively. However, the state of normal functioning of the thyroid gland is known as euthyroidism. Hypothyroidism, generally called Myxedema in adults can be caused by a number of diseases of the thyroid gland or can be secondary effects of pituitary gland or hypothalamus dysfunction. In case of pituitary hypothyroidism and hypothalamic hypothyroidism the patient responds to a dose of Thyroid stimulating hormone or Thyroxin; but in can of thyroid gland dysfunction no response to Thyroxin is obtained (Pearce et al., 2013). Symptoms of hypothyroidism may include markedly decreased basal metabolic rate, coarse and sparse hair, dry and yellow skin and low tolerance of cold. Hyperthyroidism is more common in women than in men and is often caused by self-antibodies that stimulate the receptor for thyroid hormones. This results in non-functioning of thyroid hormone in spite of being present in the circulating blood. Both the thyroid hormone secretion are substantially increased and due to over activity of the thyroid gland, it gets enlarged leading to a condition called Goitre (Biondi et al., 2015). However, as thyroid hormone levels remain adequate in the circulating blood Thyroid stimulating hormone is maintained at a low level due to feedback inhibition of the same. Some of the significant symptoms of hyperthyroidism are weight loss, low tolerance of heat, increased blood pressure, and a markedly increase in the basal metabolic rate of the body. References Ortiga?Carvalho, T. M., Chiamolera, M. I., Pazos?Moura, C. C., Wondisford, F. E. (2016). Hypothalamus?Pituitary?Thyroid Axis.Comprehensive Physiology. Pearce, S. H., Brabant, G., Duntas, L. H., Monzani, F., Peeters, R. P., Razvi, S., Wemeau, J. L. (2013). 2013 ETA guideline: management of subclinical hypothyroidism.European thyroid journal,2(4), 215-228. Biondi, B., Bartalena, L., Cooper, D. S., Hegeds, L., Laurberg, P., Kahaly, G. J. (2015). The 2015 European Thyroid Association guidelines on diagnosis and treatment of endogenous subclinical hyperthyroidism.European thyroid journal,4(3), 149-163. Arancibia-Carcamo, I. L., Attwell, D. (2014). The node of Ranvier in CNS pathology.Acta neuropathologica,128(2), 161-175. Dendrou, C. A., Fugger, L., Friese, M. A. (2015). Immunopathology of multiple sclerosis.Nature reviews. Immunology,15(9), 545.